Catalysis by Enzymes immobilized on Tuned Mesoporous Silica

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Catalysis by Enzymes immobilized on Tuned Mesoporous Silica

Show simple item record Reni, George Dr.Sugunan, S 2014-08-18T05:13:58Z 2014-08-18T05:13:58Z 2013-05
dc.description Department of Applied Chemistry Cochin University of Science and Technology en_US
dc.description.abstract Mesoporous silica nanoparticles provide a non-invasive and biocompatible delivery platform for a broad range of applications in therapeutics, pharmaceuticals and diagnosis. Additionally, mesoporous silica materials can be synthesized together with other nanomaterials to create new nanocomposites, opening up a wide variety of potential applications. The ready functionalization of silica materials makes them ideal candidates for bioapplications and catalysis. These properties of mesoporous silica like high surface areas, large pore volumes and ordered pore networks allow them for higher loading of drugs or biomolecules. Comparative studies have been made to evaluate the different procedures; much of the research to date has involved quick exploration of new methods and supports. Requirements for different enzymes may vary, and specific conditions may be needed for a particular application of an immobilized enzyme such as a highly rigid support. In this endeavor, mesoporous silica materials having different pore size were synthesized and easily modified with active functional groups and were evaluated for the immobilization of enzymes. In this work, Aspergillus niger glucoamylase, Bovine liver catalase, Candida rugosa lipase were immobilized onto support by adsorption and covalent binding. The structural properties of pure and immobilized supports are analyzed by various characterization techniques and are used for different reactions of industrial applications. en_US
dc.description.sponsorship Cochin University of Science and Technology en_US
dc.language.iso en en_US
dc.publisher Cochin University of Science And Technology en_US
dc.subject Enzymes as biocatalyst en_US
dc.subject Immobilization en_US
dc.subject ideal enzyme supports en_US
dc.subject Enzyme immobilization en_US
dc.subject activity of enzymes en_US
dc.subject Enzyme adsorption isotherms en_US
dc.title Catalysis by Enzymes immobilized on Tuned Mesoporous Silica en_US
dc.type Thesis en_US

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