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Abstract:
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Electrochemical sensors are increasingly being investigated to perform
measurements for single or multiple analytes. Demanded by modern medical
diagnosis, advances in microfabrication technology have led to the development
of fast, sensitive and selective electrochemical sensors for drug analysis.
Electrochemical sensors for the measurement of analytes of interest in clinical
chemistry are ideally suited for these applications, due to their high sensitivity
and selectivity, simple-to-operate, rapid response time and low-cost.
As part of the present investigations eight voltammetric sensors have been
fabricated for six drugs such as PAM Chloride, Tamsulosin Hydrochloride,
Hesperidin Methyl Chalcone, Guaiphenesin, Cephalexin and Amoxicillin
trihydrate. The modification techniques adopted as part of the present work
include multiwalled carbon nanotube (MWNT) based modifications,
electropolymerization, gold nanoparticle (AuNP) based modifications and
platinum nanoparticle (PtNP) based modifications.
The thesis is divided into nine chapters |