Maheswaran, Sithambaresan; Dr.Prathapachandra Kurup,M R(Cochin University of Science and Technology, April , 2012)
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Abstract:
The unusual coordination modes of semicarbazones when bound to
metals, the wide applications and structural diversity of metal complexes of
semicarbazones provoked us to synthesize and characterize the tridentate ONO
and NNO-donor semicarbazones and their transition metal complexes. This
work is focused on the studies on complexes of three N4-phenylsemicarbazones
synthesized by changing the carbonyl compounds. This work is concerned with the studies of two new semicarbazones, 2- formylpyridine-N4-phenylsemicarbazone (HL1) and 3-ethoxysalicylaldehyde- N4-phenylsemicarbazone (H2L2) and a reported semicarbazone
2-benzoylpyridine-N4-phenylsemicarbazone (HL3) [29]. The compositions of
these semicarbazones were determined by the CHN analyses and IR, UV and
NMR spectral studies were used for the characterization of these compounds.
The molecular structure of 3-ethoxysalicylaldehyde-N4-phenylsemicarbazone
(H2L2) was obtained by single crystal X-ray diffraction studies. Also, we have
synthesized Cu(II), Cd(II), Zn(II) and Ni(II) complexes of these three
semicarbazones. The complexes were characterized by various spectroscopic
techniques, magnetic and conductivity studies. We could isolate single crystals
of some complexes of all metals suitable for X-ray diffraction studies. This
thesis is divided into six chapters.
Description:
Department of Applied Chemistry, Cochin University of Science and Technology
Maheswaran Sithambaresan; Dr. M. R. Prathapachandra Kurup(Cochin University of Science and Technology, April 18, 2012)
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Abstract:
The work embodied in this thesis was carried out by the author in the
Department of Applied Chemistry, CUSAT, Kochi, during the period 2009-2012.
The thesis is an introduction to our attempts to evaluate the coordination behavior
of some compounds of our interest. The biological activities of semicarbazones
and their metal complexes have been an active area of research during the past
years because of their significant role in naturally occurring biological systems.
Tridentate NNO and ONO semicarbazone systems formed from heterocyclic and
aromatic carbonyl compounds and their transition metal complexes are wellauthenticated
compounds in this field and their synthesis, crystal structures and
spectral studies are well desirable. Hence, we decided to develop a research
program aimed at the syntheses, crystal structures and spectral studies of new N4-
phenylsemicarbazones derived from 2-formylpyridine and 3-ethoxysalicylaldehyde
and their transition metal complexes and new transition metal complexes of 2-
benzoylpyridine-N4-phenylsemicarbazone. In addition to various physicochemical
methods of analysis, single crystal X-ray diffraction studies were also
used for the characterization of the complexes.