Finla, Chathu; Dr. Paulose, C S(Cochin University of Science and Technology, February , 2007)
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Abstract:
In the present work, the role of oxygen, epinephrine and glucose
supplementation in regulating neurotransmitter contents, adrenergic and glutamate
receptor binding parameters in the cerebral cortex of experimental groups of neonatal
rats were investigated. The study of neurotransmitters and their receptors in the
cerebral cortex and the EEG pattern in the brain regions of neonatal rats were taken as
index for brain damage due to hypoxia, oxygen and epinephrine. Real-Time PCR work was done to confirm the binding parameters. Second messenger, cyclic
Adenosine Monophosphate (cAMP) was assayed to find the functional correlation of
the receptors. Behavioural studies were carried out to confirm the biochemical and
molecular studies. The efficient and timely supplementation of glucose plays a crucial
role in correcting the molecular changes due to hypoxia, oxygen and epinephrine. The
addictive neuronal damage effect due to oxygen and epinephrine treatment is another
important observation. The corrective measures from the molecular study brought to
practice will lead to maintain healthy intellectual capacity during the later
developmental stages, which has immense clinical significance in neonatal care.
Description:
Department of Biotechnology, Cochin
University of Science and Technology
Clara, Margret Katticaran; Dr.Mohammed Salih,K Y(Cochin University Of Science And Technology, December , 1988)
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Abstract:
Enhancement and culture of bivalves presents an opportunity
to maximise and even increase production of many growing areas. Clam
culture is less intensive both for capital and labour, involves simple farming
and management techniques and is considered an efficient means of protein
production. Clams are efficient converters of primary production and
growth rate is fast with maximum production in 5-6 months. with culture,
production is less influenced by poor recruitment. Stable production
facilitates market development. Rivalves are being increasingly used
in bio-medical research. Culture practices would ensure uninterrupted
supplies of experimental material. Paucity of biological data restricts the development of efficient management and culture techniques of bivalves. This study was undertaken with a view to provide information on some aspects of biology of the bivalve S_. scripta which have hitherto been uninvestigated.
Description:
School of Marine Sciences,
Cochin University of Science and Technology
Madhupratap,M; Dr.Rao, T S S(Cochin University of Science And Technology, August , 1976)
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Abstract:
Ecology is the study of systems at a level
in which individuals or whole organisms may be
considered elements of interaction, either among
themselves, or with a loosely organised environmental
matrix. Systems at this level are named
ecosystems, and ecology, of course, is the biology
of ecosystems" (Hargalef, 1968).
This thesis includes principally, a study on
the ecology of zooplankton of the Cochin backwaters
conducted during the years 1971-72. This monsoonal
estuarine system is particularly interesting, since
it exhibits a wide range of variations in its environmental
conditions which is naturally reflected in
the fauna also. Several publications on various
aspects of its hydrobiology have come out in the
recent past. But studies on the zooplankton of the
estuary have mostly been discontinuous either in space
or time or restricted to its groups
Description:
School of marine sciences, Cochin University of Science And Technology
Paulose,C S; Athira, Babu; Anju, T R(Indian Journal of Biochemistry and Biophysics, April , 2009)
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Abstract:
Hypoxia is one of the major causes of damage to the fetal and neonatal brain and cardiac functions. in earlier studies we have reported the brain damage caused by hypoxia and resusciation with oxygen and epinephrine and have found that glucose treatment to hypoxic rats and hypoxic rats treated with oxygen shows a reversal of brain damage. during this study the findings may have clinical significance in the proper management of heart and brain functions.